2. GPCR/G Protein Immunology/Inflammation
  3. CCR
  4. CCR3 antagonist 1

CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.

For research use only. We do not sell to patients.

CCR3 antagonist 1 Chemical Structure

CCR3 antagonist 1 Chemical Structure

CAS No. : 879399-82-3

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1 mg USD 190 In-stock
5 mg USD 425 In-stock
10 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

CCR3 antagonist 1 Related Antibodies

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1 Publications Citing Use of MCE CCR3 antagonist 1

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

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Description

CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.

IC50 & Target[1]

CCR3

 

Molecular Weight

490.42

Formula

C19H21Cl2N3O4S2
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(O)CC1=CSC(SCC(NC[C@H]2CN(CC3=CC=C(Cl)C(Cl)=C3)CCO2)=O)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (254.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0391 mL 10.1953 mL 20.3907 mL
5 mM 0.4078 mL 2.0391 mL 4.0781 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0391 mL 10.1953 mL 20.3907 mL 50.9767 mL
5 mM 0.4078 mL 2.0391 mL 4.0781 mL 10.1953 mL
10 mM 0.2039 mL 1.0195 mL 2.0391 mL 5.0977 mL
15 mM 0.1359 mL 0.6797 mL 1.3594 mL 3.3984 mL
20 mM 0.1020 mL 0.5098 mL 1.0195 mL 2.5488 mL
25 mM 0.0816 mL 0.4078 mL 0.8156 mL 2.0391 mL
30 mM 0.0680 mL 0.3398 mL 0.6797 mL 1.6992 mL
40 mM 0.0510 mL 0.2549 mL 0.5098 mL 1.2744 mL
50 mM 0.0408 mL 0.2039 mL 0.4078 mL 1.0195 mL
60 mM 0.0340 mL 0.1699 mL 0.3398 mL 0.8496 mL
80 mM 0.0255 mL 0.1274 mL 0.2549 mL 0.6372 mL
100 mM 0.0204 mL 0.1020 mL 0.2039 mL 0.5098 mL
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CCR3 antagonist 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CCR3 antagonist 1879399-82-3CCRCC chemokine receptorInhibitorinhibitorinhibit

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