CCR3 antagonist 1

Cat. No.: HY-U00331 Purity: 98.95%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.

For research use only. We do not sell to patients.

CCR3 antagonist 1 Chemical Structure

CAS No. : 879399-82-3

Size	Price	Stock	Quantity
5 mg	USD 425	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 650	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE CCR3 antagonist 1

•Bioact Mater. 2021 Jan 7;6(7):2039-2057. [Abstract]

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

Biological Activity
Purity & Documentation
References
Customer Review

Description

CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.

IC₅₀ & Target^[1]

CCR3

Molecular Weight

490.42

Formula

C₁₉H₂₁Cl₂N₃O₄S₂

CAS No.

879399-82-3

Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(O)CC1=CSC(SCC(NC[C@H]2CN(CC3=CC=C(Cl)C(Cl)=C3)CCO2)=O)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (254.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0391 mL	10.1953 mL	20.3907 mL
5 mM	0.4078 mL	2.0391 mL	4.0781 mL
10 mM	0.2039 mL	1.0195 mL	2.0391 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.95%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (245 KB) HNMR (263 KB) LCMS (86 KB)

Handling Instructions (2659 KB)

References

[1]. MORPHOLINE COMPOUND. WO 2006028284 A1

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0391 mL	10.1953 mL	20.3907 mL	50.9767 mL
	5 mM	0.4078 mL	2.0391 mL	4.0781 mL	10.1953 mL
	10 mM	0.2039 mL	1.0195 mL	2.0391 mL	5.0977 mL
	15 mM	0.1359 mL	0.6797 mL	1.3594 mL	3.3984 mL
	20 mM	0.1020 mL	0.5098 mL	1.0195 mL	2.5488 mL
	25 mM	0.0816 mL	0.4078 mL	0.8156 mL	2.0391 mL
	30 mM	0.0680 mL	0.3398 mL	0.6797 mL	1.6992 mL
	40 mM	0.0510 mL	0.2549 mL	0.5098 mL	1.2744 mL
	50 mM	0.0408 mL	0.2039 mL	0.4078 mL	1.0195 mL
	60 mM	0.0340 mL	0.1699 mL	0.3398 mL	0.8496 mL
	80 mM	0.0255 mL	0.1274 mL	0.2549 mL	0.6372 mL
	100 mM	0.0204 mL	0.1020 mL	0.2039 mL	0.5098 mL